Inverse tuning of metal binding affinity and protein stability by altering charged coordination residues in designed calcium binding proteins

doi:10.1186/1757-5036-2-11

Research article

Inverse tuning of metal binding affinity and protein stability by altering charged coordination residues in designed calcium binding proteins

Anna W Maniccia¤, Wei Yang¤, Julian A Johnson, Shunyi Li, Harianto Tjong, Huan-Xiang Zhou, Lev A Shaket and Jenny J Yang*

* Corresponding author: Jenny J Yang chejjy@langate.gsu.edu
¤ Equal contributors

PMC Biophysics 2009, 2:11 doi:10.1186/1757-5036-2-11

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Inverse tuning of metal binding affinity and protein stability by altering charged coordination residues in designed calcium binding proteins

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Inverse tuning of metal binding affinity and protein stability by altering charged coordination residues in designed calcium binding proteins